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Article

Characterization of human killer immunoglobulin-like receptors (KIRs) among healthy Saudis.

Human immunology - 1 Jun 2014

Osman Awad E, Mubasher Mohamed, ElSheikh Nezar E, AlHarthi Hanan, Al Yami Ahmed S, Rajalingam Raja, Al-Dehaimi Abdulwahid, Middleton Derek, ElGhazali Gehad

Abstract excerpt

Genes encoding KIRs vary in frequency among different populations and ethnic groups. This study investigated the KIR gene frequency distribution in 148 healthy unrelated Saudi subjects and compared the results with other published findings. All inhibitory and activating KIR genes were present at variable frequencies, with A haplotype-associated genes (KIR2DL1, -2DL3, -3DL1, and KIR2DS4) being observed at higher...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24613458
DOI: 10.1016/j.humimm.2014.02.023

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