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Thirty allele-level haplotypes centered around KIR2DL5 define the diversity in an African American population.

Immunogenetics - 1 Aug 2010

Hou Lihua, Chen Minghua, Jiang Bo, Wu DongYing, Ng Jennifer, Hurley Carolyn Katovich

Abstract excerpt

KIR2DL5 alleles were physically linked to alleles at adjacent KIR loci to define this region of KIR haplotypes in 55 gene-positive random African Americans. The majority carried KIR2DL5B. Three KIR2DL5A and six KIR2DL5B alleles that have been previously described and 11 novel KIR2DL5 alleles were identified by DNA sequencing. Novel alleles included variation that may impact promoter activity; two alleles carried...

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Source

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Identifiers

PMID: 20585770
DOI: 10.1007/s00251-010-0458-8
PMCID: PMC3485642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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