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Article

Selection kinetics during serial cell culture passage of mixtures of wild-type Autographa californica nuclear polyhedrosis virus and its recombinant Ac360-beta-gal.

The Journal of general virology - 1 Nov 1991

Huang Y S, Bobseine K L, Setzer R W, Kawanishi C Y

Abstract excerpt

Detailed analysis of the selection process in serial co-infections of cell cultures by wild-type Autographa californica nuclear polyhedrosis virus (AcNPV) strain E2 (AcNPV/E2) and Ac360-beta-gal, a genetically engineered strain, shows that the unaltered strain was clearly dominant even when it initially constituted the minority component in the inoculum. A method of calculating a selection coefficient that...

Topics

Baculoviridae
Cells, Cultured
Cloning, Molecular
Kinetics
Microscopy, Electron
Phenotype
Recombination, Genetic
Selection, Genetic
Serial Passage
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1940862
DOI: 10.1099/0022-1317-72-11-2653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1940862-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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