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Article

Competition-colonization dynamics in an RNA virus.

Proceedings of the National Academy of Sciences of the United States of America - 2 Feb 2010

Ojosnegros Samuel, Beerenwinkel Niko, Antal Tibor, Nowak Martin A, Escarmís Cristina, Domingo Esteban

Abstract excerpt

During replication, RNA viruses rapidly generate diverse mutant progeny which differ in their ability to kill host cells. We report that the progeny of a single RNA viral genome diversified during hundreds of passages in cell culture and self-organized into two genetically distinct subpopulations that exhibited the competition-colonization dynamics previously recognized in many classical ecological systems. Viral...

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Identifiers

PMID: 20080701
DOI: 10.1073/pnas.0909787107
PMCID: PMC2836666

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