Article
Competition among co-infecting potyviral chimeras with adaptive, single-nucleotide differences in HCPro: Properties, and influence of environment factors on outcomes.
PLoS pathogens - 1 Aug 2026
Makki Mongia, Fernández-Avilés María, Tenllado Francisco, Canto Tomás
Abstract excerpt
We previously showed that two natural, single-amino acid mutations in the HCPro of a potyviral chimera, separately increased virulence by enhancing either its silencing-suppression or proteolytic functions. To investigate how beneficial variants generated during infection compete with non-mutant forms, or among each other, we co-expressed them in pairs, in Nicotiana benthamiana. We assessed how variants co-exist...
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