Article
Molecular definition of a polymorphic antigen (LA45) of free HLA-A and -B heavy chains found on the surfaces of activated B and T cells.
The Journal of experimental medicine - 1 Nov 1991
Madrigal J A, Belich M P, Benjamin R J, Little A M, Hildebrand W H, Mann D L, Parham P
Abstract excerpt
A monomoprhic monoclonal antibody (LA45 antibody) reactive with "a new activation-induced surface structure on human T lymphocytes" (LA45 antigen) that resembled free class I heavy chains has recently been described (Schnabl, E., H. Stockinger, O. Majdic, H. Gaugitsch, I.J.D. Lindley, D. Maurer, A. Hajek-Rosenmayr, and W. Knapp. 1990. J. Exp. Med. 171:1431). This antibody was used to clone a class I-like heavy...
Topics
- Alleles
- Amino Acid Sequence
- Antibodies, Monoclonal
- Antibody Specificity
- Antigens, Surface
- B-Lymphocytes
- Base Sequence
- HLA-A Antigens
- HLA-B Antigens
- Humans
- Lymphocyte Activation