Article
A polymorphism in ERAP1 is associated with susceptibility to ankylosing spondylitis in a Turkish population.
Rheumatology international - 1 Nov 2013
Cinar Muhammet, Akar Hatice, Yilmaz Sedat, Simsek Ismail, Karkucak Mutlu, Sagkan Rahsan Ilıkci, Pekel Aysel, Erdem Hakan, Avci Ismail Yasar, Acikel Cengizhan, Musabak Ugur, Tunca Yusuf, Pay Salih
Abstract excerpt
We assessed the role played by the ERAP1 gene in Turkish patients with ankylosing spondylitis (AS) in terms of disease susceptibility, clinical manifestations, and disease severity. We included 150 consecutive AS patients who met the modified New York classification criteria and 150 healthy controls. We documented the presence of 10 ERAP1 single-nucleotide polymorphisms (SNPs) and HLA-B27 in these patients. ERAP1...
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