Article
Prognostic significance of transcription factor E2F-1 in bladder cancer: genotypic and phenotypic characterization.
Journal of the National Cancer Institute - 19 May 1999
Rabbani F, Richon V M, Orlow I, Lu M L, Drobnjak M, Dudas M, Charytonowicz E, Dalbagni G, Cordon-Cardo C
Abstract excerpt
BACKGROUND: We sought to identify and characterize potential alterations in E2F-1, a transcription factor that binds to the retinoblastoma protein (pRB), in bladder neoplasms and to elucidate a possible role for E2F-1 as an oncogene or a tumor suppressor gene. METHODS: Tumor samples from 133 eval...
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