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Article

Biological effect of Muller's Ratchet: distant capsid site can affect picornavirus protein processing.

Journal of virology - 1 Jul 2009

Escarmís Cristina, Perales Celia, Domingo Esteban

Abstract excerpt

Repeated bottleneck passages of RNA viruses result in accumulation of mutations and fitness decrease. Here, we show that clones of foot-and-mouth disease virus (FMDV) subjected to bottleneck passages, in the form of plaque-to-plaque transfers in BHK-21 cells, increased the thermosensitivity of th...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Foot-and-Mouth Disease Virus

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Share to Protein Processing, Post-Translational

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Source

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Identifiers

PMID: 19403672
DOI: 10.1128/JVI.00538-09
PMCID: PMC2698577

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19403672-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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