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Article

Mechanisms of temperature sensitivity of attenuated Urabe mumps virus.

Virus research - 2 Jan 2017

Schinkel Stephanie C Burke, Rubin Steven, Wright Kathryn E

Abstract excerpt

Temperature sensitivity is a phenotype often associated with attenuation of viruses. Previously, we purified several mumps variants from an incompletely attenuated Urabe strain live attenuated vaccine. Here we characterize one isolate that is sensitive to growth at high temperature. This virus wa...

Topics

Animals
Chlorocebus aethiops
Genetic Variation
Mumps virus
Polymorphism, Single Nucleotide
RNA, Viral
Temperature
Transcription, Genetic
Vero Cells
Viral Proteins
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27720824
DOI: 10.1016/j.virusres.2016.10.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-27720824-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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