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Article

Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes.

The American journal of clinical nutrition - 1 Jun 2009

Lê Kim-Anne, Ith Michael, Kreis Roland, Faeh David, Bortolotti Murielle, Tran Christel, Boesch Chris, Tappy Luc

Abstract excerpt

BACKGROUND: Both nutritional and genetic factors are involved in the pathogenesis of nonalcoholic fatty liver disease and insulin resistance. OBJECTIVE: The aim was to assess the effects of fructose, a potent stimulator of hepatic de novo lipogenesis, on intrahepatocellular lipids (IHCLs) and insulin sensitivity in healthy offspring of patients with type 2 diabetes (OffT2D)--a subgroup of individuals prone to...

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Identifiers

PMID: 19403641
DOI: 10.3945/ajcn.2008.27336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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