Article
Insulin-like growth factor 2 (IGF2 ) and IGF-binding protein 1 (IGFBP1) gene variants are associated with overfeeding-induced metabolic changes.
Diabetologia - 1 Dec 2001
Ukkola O, Sun G, Bouchard C
Abstract excerpt
AIMS/HYPOTHESIS: The aim of this study was to investigate the role of insulin-like growth factor 1 (IGF1), IGF2, IGF binding protein 1 (IGFBP1) and IGFBP3 gene variants on the metabolic changes observed in response to a 100-day overfeeding protocol conducted with 12 pairs of monozygotic twins. METHODS: Genotyping was done by PCR-RFLP and DNA sequencer methods. Body fat measurements included hydrodensitometry and...
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