Article
Expression of Mcl-1 splicing variants in clear-cell renal cancer and their correlation with histopathological parameters and prognosis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2009
Kempkensteffen Carsten, Hinz Stefan, Johannsen Manfred, Krause Hans, Magheli Ahmed, Christoph Frank, Köllermann Jens, Schrader Mark, Schostak Martin, Miller Kurt, Weikert Steffen
Abstract excerpt
BACKGROUND/AIMS: Altered expression of the Bcl-2 family member Mcl-1 has been linked to the progression and outcome of various malignancies, but its expression and potential prognostic value has yet not been investigated in clear-cell renal cell carcinomas (ccRCC). METHODS: In this study, dual-colour real-time RT-PCR was used to quantify the expression of Mcl-1 splicing variants in malignant and paired normal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
