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Inhibition of cathelicidin activity by bacterial exopolysaccharides

21 Apr 2009

Abstract excerpt

The interaction of bacterial exopolysaccharides, produced by opportunistic lung pathogens, with antimicrobial peptides of the innate primate immune system was investigated. The exopolysaccharides were produced by Pseudomonas aeruginosa, Inquilinus limosus and clinical isolates of the Burkholderia cepacia complex, bacteria that are all involved in lung infections of cystic fibrosis patients. The effects of the...

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PMID: 19400793
DOI: 10.1111/j.1365-2958.2009.06707.x

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