Article
Influence of deletions within domain II of exotoxin A on its extracellular secretion from Pseudomonas aeruginosa.
Journal of bacteriology - 1 Jul 2000
Voulhoux R, Taupiac M P, Czjzek M, Beaumelle B, Filloux A
Abstract excerpt
Pseudomonas aeruginosa is a gram-negative bacterium that secretes many proteins into the extracellular medium via the Xcp machinery. This pathway, conserved in gram-negative bacteria, is called the type II pathway. The exoproteins contain information in their amino acid sequence to allow targeting to their secretion machinery. This information may be present within a conformational motif. The nature of this...
Topics
- ADP Ribose Transferases
- Bacterial Proteins
- Bacterial Toxins
- Exotoxins
- Models, Molecular
- Mutagenesis, Insertional
- Mutation
- Periplasm
- Poly(ADP-ribose) Polymerases
- Protein Structure, Secondary
- Protein Structure, Tertiary
- Pseudomonas aeruginosa
- Sequence Deletion
- Virulence Factors