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Article

Structural basis of drug resistance by genetic variants of HIV type 1 clade c protease from India.

AIDS research and human retroviruses - 1 May 2009

Kandathil Abraham Joseph, Joseph Agnel Praveen, Kannangai Rajesh, Srinivasan Narayanaswamy, Abraham Oriapadickal Cherian, Pulimood Susanne Alexander, Sridharan Gopalan

Abstract excerpt

Using computer modeling of three-dimensional structures and structural information available on the crystal structures of HIV-1 protease, we investigated the structural effects of mutations, in treatment-naive and treatment-exposed individuals from India and postulated mechanisms of resistance in...

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Identifiers

PMID: 19400736
DOI: 10.1089/aid.2008.0102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19400736-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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