Article
The frequency of HIV-I drug resistance mutations among treatment-naive individuals at a tertiary care centre in south India.
International journal of STD & AIDS - 1 Aug 2009
Kandathil A J, Kannangai R, Abraham O C, Rupali P, Pulimood S A, Verghese V P, Grant P, Pillay D, Sridharan G
Abstract excerpt
Antiretroviral treatment (ART) use in India requires information on baseline drug resistance mutations and polymorphisms in the protease (Pr) and reverse transcriptase (RT) genes of HIV-1 strains from treatment-naïve individuals. We report resistance predictor mutations and polymorphisms in the Pr and the RT sequence of non-clade B HIV-1 strains from ART naïve individuals. The genotypic resistance assay was done...
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