Article
On the use of phylogeny-based tests to detect association between quantitative traits and haplotypes.
Genetic epidemiology - 1 Dec 2009
Bardel Claire, Danjean Vincent, Morange Pierre, Génin Emmanuelle, Darlu Pierre
Abstract excerpt
With the increasing availability of genetic data, several SNPs in a candidate gene can be combined into haplotypes to test for association with a quantitative trait. When the number of SNPs increases, the number of haplotypes can become very large and there is a need to group them together. The use of the phylogenetic relationships between haplotypes provides a natural and efficient way of grouping. Moreover, it...
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