Article
SNPs and snails and puppy dogs' tails: analysis of SNP haplotype data using the gamete competition model.
Annals of human genetics - 1 Sept 2001
Sinsheimer J S, McKenzie C A, Keavney B, Lange K
Abstract excerpt
The gamete competition model is a likelihood version of the transmission disequilibrium test (TDT) that is inspired by conditional logistic regression and the Bradley-Terry ranking procedure. In family-based association studies, both the TDT and the gamete competition model apply directly to data on a single nucleotide polymorphism (SNP). Because any given SNP has limited polymorphism, it is tempting to collect...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.