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Article

Frequent upregulation of <i>MYC</i> in plasma cell leukemia

24 Apr 2009

Abstract excerpt

Plasma cell leukemia (PCL) is a rare form of monoclonal gammopathy, which can originate de novo or evolve from multiple myeloma (MM) as a terminal leukemic phase. Previous cytogenetic studies of PCL have reported the presence of complex karyotypes with involvement of multiple unidentified chromosomal regions. We report here the analysis of 12 PCL (10 primary and two secondary) by metaphase and FISH analysis...

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PMID: 19396865
DOI: 10.1002/gcc.20670

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