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Article

Origin and dispersal of atypical aldehyde dehydrogenase ALDH2487Lys.

Gene - 15 Apr 2009

Luo Huai-Rong, Wu Gui-Sheng, Pakstis Andrew J, Tong Li, Oota Hiroki, Kidd Kenneth K, Zhang Ya-Ping

Abstract excerpt

The East Asian respond with a marked facial flushing and mild to moderate symptoms of intoxication after drinking the amounts of alcohol that has no detectable effect on European. The alcohol sensitivity in Orientals is due to a delayed oxidation of acetaldehyde by an atypical aldehyde dehydrogenase ALDH2487Lys, which is resulted from a structural mutation in gene ALDH2. The atypical ALDH2487Lys allele has been...

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Source

Identifiers

PMID: 19393179
DOI: 10.1016/j.gene.2008.12.021

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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