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Article

TNFandLTAGene, Allele, and Extended HLA Haplotype Associations with Severe Dengue Virus Infection in Ethnic Thais

24 Apr 2009

Abstract excerpt

Severe dengue virus (DENV) infection is characterized by a cascade of cytokine production, including the production of tumor necrosis factor-alpha (TNF-alpha) and lymphotoxin-alpha (LT-alpha). We have analyzed a variety of polymorphisms in the TNF and LTA genes of 435 ethnic Thais who had subclinical DENV infection, primary or secondary dengue fever (DF), or primary or secondary dengue hemorrhagic fever (DHF)....

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PMID: 19392621
DOI: 10.1086/597422

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