Article
Dopamine D2 receptor gene polymorphisms are associated with suicide attempt in the Japanese population.
Neuropsychobiology - 1 Jan 2009
Suda Akira, Kawanishi Chiaki, Kishida Ikuko, Sato Ryoko, Yamada Tomoki, Nakagawa Makiko, Hasegawa Hana, Kato Daiji, Furuno Taku, Hirayasu Yoshio
Abstract excerpt
BACKGROUND: Some reports have suggested the involvement of the D2 dopaminergic function in the expression of suicidal behavior. Here, we examined associations between suicide attempts and two kinds of functional polymorphisms in the dopamine D2 receptor (DRD2) gene, namely, TaqIA and -141C Ins/Del. METHODS: Subjects included 120 suicide attempters and 123 unrelated volunteers. Those who attempted suicide were...
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