Article
Association of alpha2A-adrenergic receptor gene polymorphism with susceptibility to suicide in Japanese females.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Aug 2008
Fukutake Masaaki, Hishimoto Akitoyo, Nishiguchi Naoki, Nushida Hideyuki, Ueno Yasuhiro, Shirakawa Osamu, Maeda Kiyoshi
Abstract excerpt
OBJECTIVES: It has been suggested that noradrenergic system abnormalities are involved in suicide. Postmortem brain studies have shown that molecular and functional alterations in alpha2A-adrenergic receptor-induced signal transduction are associated with suicide and depression. Recently, a singl...
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