Article
Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases.
Genes and immunity - 1 Sept 2009
Yu X, Wieczorek S, Franke A, Yin H, Pierer M, Sina C, Karlsen T H, Boberg K M, Bergquist A, Kunz M, Witte T, Gross W L, Epplen J T, Alarcón-Riquelme M E, Schreiber S, Ibrahim S M
Abstract excerpt
We reported earlier that two mitochondrial gene polymorphisms, UCP2 -866 G/A (rs659366) and mtDNA nt13708 G/A (rs28359178), are associated with multiple sclerosis (MS). Here we aim to investigate whether these functional polymorphisms contribute to other eight chronic inflammatory diseases, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Wegener' granulomatosis (WG), Churg-Strauss...
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