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Article

Analyses of conditions for KMSSS loop in tyrosyl-tRNA synthetase by building a mutant library.

Journal of biochemistry - 1 Aug 2009

Kamijo Shunsuke, Fujii Akihiko, Onodera Kenji, Wakabayashi Kenichi

Abstract excerpt

The KMSKS motif is the ATP binding motif for aminoacylation process of class I aminoacyl-tRNA synthetases. Although researches based on natural proteins inform us about the contribution of natural amino acid sequences for the catalysis, they have difficulties in discussing the other alternative sequences and prohibited sequences for the motif to maintain the catalytic ability. In order to reveal such the...

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PMID: 19386777
DOI: 10.1093/jb/mvp063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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