Genetic diversity of Plasmodium malariae in sub-Saharan Africa: a two-marker genotyping approach for molecular epidemiological studies.

doi:10.3389/fcimb.2024.1405198

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Genetic diversity of Plasmodium malariae in sub-Saharan Africa: a two-marker genotyping approach for molecular epidemiological studies.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Rodi Miriam, Kawecka Katarzyna, Stephan Laura, Berner Lilith, Medina Martha Salinas, Lalremruata Albert, Woldearegai Tamirat Gebru, Matsiegui Pierre Blaise, Groger Mirjam, Manego Rella Zoleko, Ekoka Mbassi Dorothea, Mombo-Ngoma Ghyslain, Agnandji Selidji Todagbe, Ramharter Michael, Mordmüller Benjamin, Inoue Juliana, Held Jana

Abstract excerpt

Introduction: Plasmodium malariae is the most common non-falciparum species in sub-Saharan Africa. Despite this, data on its genetic diversity is scarce. Therefore, we aimed to establish a P. malariae genotyping approach based on size polymorphic regions that can be easily applied in molecular epidemiological studies. Methods: Four potential genotyping markers, Pm02, Pm09, P. malariae thrombospondin-related...

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PMID: 39108983
DOI: 10.3389/fcimb.2024.1405198
PMCID: PMC11301411

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