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Article

Functional identification of the promoter of SLC4A5, a gene associated with cardiovascular and metabolic phenotypes in the HERITAGE Family Study.

European journal of human genetics : EJHG - 1 Nov 2009

Stütz Adrian M, Teran-Garcia Margarita, Rao D C, Rice Treva, Bouchard Claude, Rankinen Tuomo

Abstract excerpt

The sodium bicarbonate cotransporter gene SLC4A5, associated earlier with cardiovascular phenotypes, was tested for associations in the HERITAGE Family Study, and possible mechanisms were investigated. Twelve tag-single nucleotide polymorphisms (SNPs) covering the SLC4A5 gene were analyzed in 276 Black and 503 White healthy, sedentary subjects. Associations were tested using a variance components-based (QTDT)...

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Identifiers

PMID: 19384345
DOI: 10.1038/ejhg.2009.64
PMCID: PMC2766005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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