Article
Association of SLC34A2 variation and sodium-lithium countertransport activity in humans and baboons.
American journal of hypertension - 1 Mar 2009
Zheng Xiaojing, Kammerer Candace M, Cox Laura A, Morrison Alanna, Turner Stephen T, Ferrell Robert E
Abstract excerpt
BACKGROUND: Sodium-lithium countertransport (SLC) activity, an intermediate phenotype of essential hypertension, has been linked to a region of baboon chromosome 5, homologous to human chromosome 4p. Human SLC34A2, located at chromosome 4p15.1-p15.3, is a positional candidate gene for SLC. The specific aim of this study was to identify genetic variants of the SLC34A2 gene in both baboon and human, and to examine...
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