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Article

Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 May 2011

Bouchard Claude, Sarzynski Mark A, Rice Treva K, Kraus William E, Church Timothy S, Sung Yun Ju, Rao D C, Rankinen Tuomo

Abstract excerpt

Low cardiorespiratory fitness is a powerful predictor of morbidity and cardiovascular mortality. In 473 sedentary adults, all whites, from 99 families of the Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) Family Study, the heritability of gains in maximal O(2) uptake (VO(2max)) after exposure to a standardized 20-wk exercise program was estimated at 47%. A genome-wide association study based on...

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Identifiers

PMID: 21183627
DOI: 10.1152/japplphysiol.00973.2010
PMCID: PMC3098655

Genes

ZIC4
ACSL1
CAMTA1
DAAM1
KCNH8
NDN
PRDM1
RGS18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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