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Article

Sodium bicarbonate cotransporter polymorphisms are associated with baseline and 10-year follow-up blood pressures.

Hypertension (Dallas, Tex. : 1979) - 1 Mar 2006

Hunt Steven C, Xin Yuanpei, Wu Lily L, Cawthon Richard M, Coon Hilary, Hasstedt Sandra J, Hopkins Paul N

Abstract excerpt

The NaHCO3 cotransporter gene (SLC4A5) on chromosome 2 encodes a protein that transports sodium and bicarbonate across the cell membrane and regulates cellular pH. The National Heart, Lung, and Blood Institute Family Blood Pressure Program found linkage of blood pressure-related traits to the chromosomal region containing SLC4A5 and phenotype associations with single nucleotide polymorphisms (SNPs) in this gene....

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Identifiers

PMID: 16365189
DOI: 10.1161/01.HYP.0000196949.26088.3c

Genes

DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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