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Article

Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A.

Journal of cell science - 15 May 2009

Fernandez-Martinez Javier, Vela Eva M, Tora-Ponsioen Mireille, Ocaña Oscar H, Nieto M Angela, Galceran Juan

Abstract excerpt

Notch signalling is used throughout the animal kingdom to spatially and temporally regulate cell fate, proliferation and differentiation. Its importance is reflected in the dramatic effects produced on both development and health by small variations in the strength of the Notch signal. The Down-syndrome-associated kinase DYRK1A is coexpressed with Notch in various tissues during embryonic development. Here we...

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Identifiers

PMID: 19383720
DOI: 10.1242/jcs.044354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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