Article
Liability to substance use disorders: 1. Common mechanisms and manifestations.
Neuroscience and biobehavioral reviews - 1 Oct 2003
Vanyukov Michael M, Tarter Ralph E, Kirisci Levent, Kirillova Galina P, Maher Brion S, Clark Duncan B
Abstract excerpt
Variation in the risk for and severity of substance use disorders (SUD) in the population is caused by multiple organismic (genetic, biochemical, psychological) and environmental factors. Whereas drug- or drug-class-specific liability mechanisms exist, a substantial proportion of variance in the risk is shared between specific liabilities, reflecting mechanisms that determine common liability to SUD. Data from...
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