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Article

epg-1 functions in autophagy-regulated processes and may encode a highly divergent Atg13 homolog in C. elegans.

Autophagy - 1 Jul 2009

Tian E, Wang Fuxin, Han Jinghua, Zhang Hong

Abstract excerpt

Autophagy is an evolutionarily conserved intracellular catabolic system for degradation of long-lived proteins or damaged organelles. In this study, we have identified and characterized a new gene, epg-1, that plays a role in the autophagy pathway in C. elegans. Loss of function of epg-1 causes defects in various autophagy-regulated processes, including degradation of aggregate-prone proteins and optimal survival...

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PMID: 19377305
DOI: 10.4161/auto.5.5.8624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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