Article
Transcriptome and functional analysis of the eukaryotic-type serine/threonine kinase PknB in Staphylococcus aureus.
Journal of bacteriology - 1 Jul 2009
Donat Stefanie, Streker Karin, Schirmeister Tanja, Rakette Sonja, Stehle Thilo, Liebeke Manuel, Lalk Michael, Ohlsen Knut
Abstract excerpt
The function of the Staphylococcus aureus eukaryotic-like serine/threonine protein kinase PknB was investigated by performing transcriptome analysis using DNA microarray technology and biochemical assays. The transcriptional profile revealed a strong regulatory impact of PknB on the expression of genes encoding proteins which are involved in purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, and...
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