Article
Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases.
PloS one - 4 Feb 2010
Miller Malgorzata, Donat Stefanie, Rakette Sonja, Stehle Thilo, Kouwen Thijs R H M, Diks Sander H, Dreisbach Annette, Reilman Ewoud, Gronau Katrin, Becher Dörte, Peppelenbosch Maikel P, van Dijl Jan Maarten, Ohlsen Knut
Abstract excerpt
In eukaryotic cell types, virtually all cellular processes are under control of proline-directed kinases and especially MAP kinases. Serine/threonine kinases in general were originally considered as a eukaryote-specific enzyme family. However, recent studies have revealed that orthologues of eukaryotic serine/threonine kinases exist in bacteria. Moreover, various pathogenic species, such as Yersinia and...
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