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Article

Evolution of transmembrane protein kinases implicated in coordinating remodeling of gram-positive peptidoglycan: inside versus outside.

Journal of bacteriology - 1 Nov 2006

Jones Greg, Dyson Paul

Abstract excerpt

Members of a family of serine/threonine protein kinases (STPKs), unique to gram-positive bacteria, comprise an intracellular kinase domain and reiterated extracellular PASTA (for "penicillin-binding protein and serine/threonine kinase associated") domains. PASTA domains exhibit low affinity for beta-lactam antibiotics that are structurally similar to their likely normal ligands: stem peptides of unlinked...

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Share to Conserved Sequence
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Penicillin-Binding Proteins

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Source

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Identifiers

PMID: 16936012
DOI: 10.1128/JB.00800-06
PMCID: PMC1636289

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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