Article
Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes.
Gastroenterology - 1 Jun 2009
Watanabe Yoshiyuki, Kim Hyun Soo, Castoro Ryan J, Chung Woonbok, Estecio Marcos R H, Kondo Kimie, Guo Yi, Ahmed Saira S, Toyota Minoru, Itoh Fumio, Suk Ki Tae, Cho Mee-Yon, Shen Lanlan, Jelinek Jaroslav, Issa Jean-Pierre J
Abstract excerpt
BACKGROUND & AIMS: Aberrant DNA methylation is an early and frequent process in gastric carcinogenesis and could be useful for detection of gastric neoplasia. We hypothesized that methylation analysis of DNA recovered from gastric washes could be used to detect gastric cancer. METHODS: We studied...
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