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RNF180 Suppresses Methylation of ADAMTS9 DNA Promotor by Ubiquitinating DNMT3A Inhibiting Metastasis in Gastric Cancer

2020-05-29

Abstract excerpt

BACKGROUND: A disintegrin-like and metalloprotease with thrombospondin type 1 motif 9 (ADAMTS9) is hypermethylated and inhibits the proliferation of various cancers. In this study, we demonstrated that the expression of ADAMTS9 was associated with the lymphatic metastasis of gastric cancer (GC) and elucidated the down- and upstream molecular pathways in GC progression. METHODS: The study explored the expression le...

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Literature Corpus work
d647efce-5203-5ce3-91c6-f07c19d2c8c1
DOI
10.21203/rs.3.rs-30779/v1
Open publication

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RNF180 Suppresses Methylation of ADAMTS9 DNA Promotor by Ubiquitinating DNMT3A Inhibiting Metastasis in Gastric CancerDOI 10.21203/rs.3.rs-30779/v1
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