Article
Prediction of the risk for gastric cancer using candidate methylation markers in the non-neoplastic gastric mucosae.
The Journal of pathology - 1 Mar 2012
Shin Cheol Min, Kim Nayoung, Park Ji Hyun, Kang Gyeong Hoon, Kim Joo Sung, Jung Hyun Chae, Song In Sung
Abstract excerpt
Aberrant DNA methylation is frequently found during gastric carcinogenesis. Recently, we identified potential methylation markers important for Helicobacter pylori-induced gastric carcinogenesis using an Illumina methylation chip assay. In this study, we evaluated the candidate genes as markers for gastric cancer (GC) in a large Korean population. DNA methylation of PTPN6, MOS, DCC, CRK, and VAV1 was evaluated in...
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