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Article

Frequency of alpha-globin gene triplications and their interaction with beta-thalassemia mutations.

Hemoglobin - 1 Jan 2009

Giordano Piero C, Bakker-Verwij Margaretha, Harteveld Cornelis L

Abstract excerpt

Our protocol for specialized diagnostics includes routine alpha-globin gene analysis for all blood samples referred to our diagnostic laboratory. alpha-Globin gene triplication is found to be present in more than 1% of samples tested. Since all cases with single alpha-gene triplications are associated with normal hematological parameters, we assume that preselection does not bias our observation and that...

Topics

Cohort Studies
Female
Gene Amplification
Hematologic Tests
Humans
Male
Phenotype
alpha-Globins
beta-Thalassemia

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19373588
DOI: 10.1080/03630260902827684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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