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The carrier frequency of α-globin gene triplication in an Iranian population with normal or borderline hematological parameters.

Hemoglobin - 1 Jan 2011

Moosavi Seyedeh Fatemeh, Amirian Azam, Zarbakhsh Behnaz, Kordafshari Alireza, Mirzahoseini Hasan, Zeinali Sirous, Karimipoor Morteza

Abstract excerpt

The -α(3.7) rightward deletion is the most frequent α-globin mutation worldwide, while frequencies of the ααα(anti 3.7) triplication are only sporadically known. Carriers of the ααα(anti 3.7) triplication show no clinical symptoms or significant hematological changes, but co-inheritance with β-thalassemia (β-thal) has been reported to worsen the clinical and hematological features of the patient as well as the...

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PMID: 21797699
DOI: 10.3109/03630269.2011.571527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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