Article
Age at onset of bilateral breast cancer, the presence of hereditary BRCA1, BRCA2, CHEK2 gene mutations and positive family history of cancer.
Onkologie - 1 Apr 2009
Skasko Elzbieta, Kluska Anna, Niwińska Anna, Kwiatkowska Ewa, Bałabas Aneta, Piatkowska Magdalena, Dabrowska Michalina, Nowakowska Dorota, Pieńkowski Tadeusz
Abstract excerpt
BACKGROUND: Our research focused on the relations between the age at onset of bilateral breast cancer and the prevalence of selected hereditary BRCA1, BRCA2 and CHEK2 gene mutations with reference to their positive family history of cancer. METHODS: The DNA of peripheral blood lymphocytes of patients was examined for the presence of selected hereditary mutations in the BRCA1, BRCA2 and CHEK2 genes, using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.