Site frequency spectra from genomic SNP surveys.

doi:10.1016/j.tpb.2009.04.003

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Article

Site frequency spectra from genomic SNP surveys.

Theoretical population biology - 1 Jun 2009

Ganapathy Ganeshkumar, Uyenoyama Marcy K

Abstract excerpt

Genomic survey data now permit an unprecedented level of sensitivity in the detection of departures from canonical evolutionary models, including expansions in population size and selective sweeps. Here, we examine the effects of seemingly subtle differences among sampling distributions on goodness of fit analyses of site frequency spectra constructed from single nucleotide polymorphisms. Conditioning on the...

Topics

Alleles
Genome
Models, Theoretical
Polymorphism, Single Nucleotide

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Identifiers

PMID: 19371756
DOI: 10.1016/j.tpb.2009.04.003
PMCID: PMC2736640

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