Article
An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Mar 2009
Janssens A Cecile J W, González-Zuloeta Ladd Angela M, López-Léon Sandra, Ioannidis John P A, Oostra Ben A, Khoury Muin J, van Duijn Cornelia M
Abstract excerpt
PURPOSE: Consortia of investigators currently compile sufficiently large sample sizes to investigate the effects of low-risk susceptibility genetic variants. It is not clear how the results obtained by consortia compare with those derived from meta-analyses of published studies. METHODS: We perfo...
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