Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis.

International journal of cancer - 15 Mar 2009

Bogan Christina, Chen Jin, O'Sullivan M Gerard, Cormier Robert T

Abstract excerpt

The Eph receptor A2 (EphA2) is overexpressed in a range of human epithelial cancers, a phenotype that is associated with cancer cell proliferation, progression and angiogenesis. Mouse models of mammary neoplasia have confirmed the role of EphA2 as mice carrying a knockout allele of EphA2 were res...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Chromosomes, Human, Pair 1
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Intestines

Share to Mice, Inbred C57BL

Share to Neoplasm Metastasis

Share to Neoplasms

Source

Identifiers

PMID: 19089910
DOI: 10.1002/ijc.24083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19089910-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis.PMID 19089910Read ↗

EphB receptor activity suppresses colorectal cancer progression.Semantic proximity Read ↗

Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.Semantic proximity Read ↗

Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc Min/+ miceSemantic proximity Read ↗

Wnt signalling in the mouse intestine.Semantic proximity Read ↗

Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesisSemantic proximity Read ↗

The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine.Semantic proximity Read ↗

Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenic KRas in promoting lung adenocarcinoma.Semantic proximity Read ↗

Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer.Semantic proximity Read ↗

HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal Epithelium.Semantic proximity Read ↗

EphA2 Receptor Tyrosine Kinase as a Promising Target for Cancer TherapeuticsSemantic proximity Read ↗

EphB6 overexpression and Apc mutation together promote colorectal cancer.Semantic proximity Read ↗

Genetically induced mouse model for colon-specific epithelial cell tumorigenesis driven by loss of K8 and ApcSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.