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Article

N-cadherin prodomain cleavage regulates synapse formation in vivo.

Developmental neurobiology - 1 Jul 2009

Latefi Nazlie S, Pedraza Liliana, Schohl Anne, Li Ziwei, Ruthazer Edward S

Abstract excerpt

Cadherins are initially synthesized bearing a prodomain that is thought to limit adhesion during early stages of biosynthesis. Functional cadherins lack this prodomain, raising the intriguing possibility that cells may utilize prodomain cleavage as a means to temporally or spatially regulate adhesion after delivery of cadherin to the cell surface. In support of this idea, immunostaining for the prodomain of...

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Identifiers

PMID: 19365814
DOI: 10.1002/dneu.20718
PMCID: PMC2744366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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