Article
Cholesteryl ester transfer protein and hepatic lipase gene polymorphisms: effects on hepatic mRNA levels, plasma lipids and carotid atherosclerosis.
Atherosclerosis - 1 Jun 2011
Soyal Selma M, Sandhofer Anton, Hahne Penelope, Oberkofler Hannes, Felder Thomas, Iglseder Bernhard, Miller Karl, Krempler Franz, Patsch Josef R, Paulweber Bernhard, Patsch Wolfgang
Abstract excerpt
OBJECTIVE: HDL modifying effects of cholesteryl ester transfer protein (CETP) and hepatic lipase (LIPC) depend in part on each other. We studied associations of CETP-Taq1B and -514C>T-LIPC polymorphisms with hepatic mRNA levels, and their combined effects on plasma lipids and carotid atherosclerosis. METHODS: We genotyped the CETP-Taq1B and the -514C>T-LIPC polymorphisms in 67 obese women in whom hepatic CETP and...
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