Article
A large-scale association study to assess the impact of known variants of the human INHA gene on premature ovarian failure.
Human reproduction (Oxford, England) - 1 Aug 2009
Corre Tanguy, Schuettler Julia, Bione Silvia, Marozzi Anna, Persani Luca, Rossetti Raffaella, Torricelli Francesca, Giotti Irene, Vogt Peter, Toniolo Daniela
Abstract excerpt
BACKGROUND: Three variants of the human INHA gene have been reported to be associated with premature ovarian failure (POF) in case-control studies involving a small number of patients and controls. Since inhibin has a fundamental role in the control of ovarian function, it is important to establish the relevance of the reported variants for disease risk. METHODS: Three independent POF cohorts, recruited in...
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