Article
INHA promoter polymorphisms are associated with premature ovarian failure.
Molecular human reproduction - 1 Nov 2005
Harris Sarah E, Chand Ashwini L, Winship Ingrid M, Gersak Ksenija, Nishi Yoshihiro, Yanase Toshihiko, Nawata Hajime, Shelling Andrew N
Abstract excerpt
Inhibin is an important glycoprotein that is involved in folliculogenesis. INHA, the gene encoding the inhibin alpha subunit, was recently proposed as a candidate for premature ovarian failure (POF), a syndrome that leads to the cessation of ovarian function under the age of 40 years. 70 POF patients and 70 controls were screened for the previously identified INHA -16C>T transition mutation. The T allele was...
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